Continuous integrated antibody precipitation with two‐stage tangential flow microfiltration enables constant mass flow

Towards Integrated Continuous-Flow Chemical Reactors

A device for rapid mixing of two solutions is presented. As the main mechanism for mixing is diffusional mass transport, the ̄ow has to be split into several laminae which are narrower than the capillary width. Complete mixing is achieved within a few seconds in a ̄ow-through device with a channel system that is 600mm wide at its narrowest spot.

Continuous-flow fast atom bombardment mass spectrometry.

The continuous-flow fast atom bombardment probe performs equally well with or without a high-performance liquid chromatography column producing clean spectra containing little or no background noise. Its function as a liquid chromatography-mass spectrometry interface for labile and involatile samples has been illustrated with reference to dansylated amino acids. The versatility of the new probe...

Influence of Residence-time Distribution on a Surface-renewal Model of Constant-pressure Cross-flow Microfiltration

This work examines the influence of the residence-time distribution (RTD) of surface elements on a model of cross-flow microfiltration that has been proposed recently (Hasan et al., 2013). Along with the RTD from the previous work (Case 1), two other RTD functions (Cases 2 and 3) are used to develop theoretical expressions for the permeate-flux decline and cake buildup in the filter as a functi...

A continuous-flow C. elegans sorting system with integrated optical fiber detection and laminar flow switching.

We present a high-throughput continuous-flow C. elegans sorting device that works based on integrated optical fiber detection and laminar flow switching. Two types of genetically engineered nematodes are allowed to flow into the device and their genotypes are detected based on their fluorescence, without the need for immobilization, by integrated optical fibers. A novel dynamic fluidic switch s...

Furrow geometry nnder surge and continuous flow